J. Brian Houston

HUMAN UDP-GLUCURONOSYLTRANSFERASES: ISOFORM SELECTIVITY AND KINETICS OF 4-METHYLUMBELLIFERONE AND 1-NAPHTHOL GLUCURONIDATION, EFFECTS OF ORGANIC SOLVENTS, AND INHIBITION BY DICLOFENAC AND PROBENECID

Verawan Uchaipichat, Peter I. Mackenzie, Xiao-Hui Guo et al. · Drug Metabolism and Disposition · 2004 · 333 citations

Prediction of Human Drug Clearance from in Vitro and Preclinical Data Using Physiologically Based and Empirical Approaches

Kiyomi Ito, J. Brian Houston · Pharmaceutical Research · 2005 · 255 citations

Pharmacokinetic Modeling, Preclinical Drug Evaluation, Human Drug Clearance +9

Comparison of the Use of Liver Models for Predicting Drug Clearance Using in Vitro Kinetic Data from Hepatic Microsomes and Isolated Hepatocytes

Kiyomi Ito, J. Brian Houston · Pharmaceutical Research · 2004 · 224 citations

Hepatology, Drug Clearance Using, Medicine +14

Evaluation of Cryopreserved Human Hepatocytes as an Alternative in Vitro System to Microsomes for the Prediction of Metabolic Clearance

Hayley S. Brown, Michael J. Griffin, J. Brian Houston · Drug Metabolism and Disposition · 2006 · 208 citations

ISOFORM SELECTIVITY AND KINETICS OF MORPHINE 3- AND 6-GLUCURONIDATION BY HUMAN UDP-GLUCURONOSYLTRANSFERASES: EVIDENCE FOR ATYPICAL GLUCURONIDATION KINETICS BY UGT2B7

Andrew N. Stone, Peter I. Mackenzie, Aleksandra Galetin et al. · Drug Metabolism and Disposition · 2003 · 203 citations