Kiyomi Ito

Prediction of Human Drug Clearance from in Vitro and Preclinical Data Using Physiologically Based and Empirical Approaches

Kiyomi Ito, J. Brian Houston · Pharmaceutical Research · 2005 · 257 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Comparison of the Use of Liver Models for Predicting Drug Clearance Using in Vitro Kinetic Data from Hepatic Microsomes and Isolated Hepatocytes

Kiyomi Ito, J. Brian Houston · Pharmaceutical Research · 2004 · 226 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

CYP3A4 Substrate Selection and Substitution in the Prediction of Potential Drug-Drug Interactions

Aleksandra Galetin, Kiyomi Ito, David Hallifax et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 156 citations

Medicine, Pharmacokinetics, Pharmacology +15

PREDICTION OF THE IN VIVO INTERACTION BETWEEN MIDAZOLAM AND MACROLIDES BASED ON IN VITRO STUDIES USING HUMAN LIVER MICROSOMES

Kiyomi Ito, Kanako Ogihara, Shin-ichi Kanamitsu et al. · Drug Metabolism and Disposition · 2003 · 150 citations

Medicine, Pharmacokinetics, Pharmacology +17

Prediction of<i>in vivo</i>drug–drug interactions from<i>in vitro</i>data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant

Hayley S. Brown, Kiyomi Ito, Aleksandra Galetin et al. · British Journal of Clinical Pharmacology · 2005 · 148 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17