Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models - Concepedia

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Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models

DOI Full Paper Access

197

Citations

44

References

2012

Year

Li Shen, Michael J. Ciesielski, Swathi Ramakrishnan, Kiersten Marie Miles, Leigh Ellis, Paula Sotomayor, Protul Shrikant, Robert A. Fenstermaker

Abstract

These results demonstrate a novel immunomodulatory effect of class I HDAC inhibition and provide a rationale for the clinical testing of entinostat to enhance cancer immunotherapy.

References

	Year	Citations

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