Protul Shrikant

Tumor-infiltrating NY-ESO-1–specific CD8 ⁺ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

Junko Matsuzaki, Sacha Gnjatic, Paulette Mhawech‐Fauceglia et al. · Proceedings of the National Academy of Sciences · 2010 · 836 citations · Full text

The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

Rajesh R. Rao, Qingsheng Li, Kunle Odunsi et al. · Immunity · 2010 · 630 citations · Full text

Signal Transduction, Adaptive Immune System, Receptor Tyrosine Kinase +10

LAG3 and PD1 co-inhibitory molecules collaborate to limit CD8+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model

Ruea-Yea Huang, Cheryl Eppolito, Shashikant Lele et al. · Oncotarget · 2015 · 311 citations · Full text

CTLA-4 Blockade Reverses CD8+ T Cell Tolerance to Tumor by a CD4+ T Cell– and IL-2-Dependent Mechanism

Protul Shrikant, Alexander Khoruts, Matthew F. Mescher · Immunity · 1999 · 282 citations · Full text

Cancer Immunosurveillance, Cd4+ T Cell–, Immunology +13

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

Rajesh R. Rao, Qingsheng Li, Melanie Gubbels Bupp et al. · Immunity · 2012 · 279 citations · Full text

Immunological Memory, Transcriptional Regulation, Systems Biology +8