Matthew F. Mescher

Inflammatory Cytokines Provide a Third Signal for Activation of Naive CD4+ and CD8+ T Cells

Julie Curtsinger, Clint S. Schmidt, Anna Mondino et al. · The Journal of Immunology · 1999 · 604 citations · Full text

Cd4+ Cells, T-regulatory Cell, Immune Regulation +18

Cutting Edge: Type I IFNs Provide a Third Signal to CD8 T Cells to Stimulate Clonal Expansion and Differentiation

Julie Curtsinger, Javier O. Valenzuela, Pujya Agarwal et al. · The Journal of Immunology · 2005 · 601 citations · Full text

Signal 3 Determines Tolerance versus Full Activation of Naive CD8 T Cells

Julie Curtsinger, Debra C. Lins, Matthew F. Mescher · The Journal of Experimental Medicine · 2003 · 498 citations · Full text

CTLA-4 Blockade Reverses CD8+ T Cell Tolerance to Tumor by a CD4+ T Cell– and IL-2-Dependent Mechanism

Protul Shrikant, Alexander Khoruts, Matthew F. Mescher · Immunity · 1999 · 282 citations · Full text

Cancer Immunosurveillance, Cd4+ T Cell–, Immunology +13

CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine

Julie Curtsinger, Christopher M. Johnson, Matthew F. Mescher · The Journal of Immunology · 2003 · 277 citations

Lymphocyte Development, Adaptive Immune System, T-regulatory Cell +19