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CTLA-4 Blockade Reverses CD8+ T Cell Tolerance to Tumor by a CD4+ T Cell– and IL-2-Dependent Mechanism

Cancer ImmunosurveillanceCd4+ T Cell–ImmunologyTumor ImmunityIl-2-dependent MechanismAutoimmunityT Cell ImmunityCd4 T Cell ResponsesSelf-toleranceTolerance InductionCellular Immune ResponseImmunotherapyMedicineCell BiologyRegulatory T Cell BiologyT Cell Biology