Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

Shin Onizuka, Isao Tawara, Jun Shimizu, +3

PubMed

ImmunologyImmune RegulationPathologyImmunoeditingMurine Tumors +20

Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in mice

Pavan Reddy, Yaping Sun, Tomomi Toubai, +12

Journal of Clinical Investigation

Extracorporeal photopheresis reverses experimental graft-versus-host disease through regulatory T cells

Erin Gatza, Clare Rogers, Shawn G. Clouthier, +5

Blood

Interleukin-6 Modulates Graft-versus-Host Responses after Experimental Allogeneic Bone Marrow Transplantation

Isao Tawara, Motoko Koyama, Chen Liu, +11

Clinical Cancer Research

Reduced Cd4+Cd25+ T cells in patients with idiopathic thrombocytopenic purpura

Miho Sakakura, Hideo Wada, Isao Tawara, +4

Thrombosis Research

ThrombopoiesisThrombosisAutoimmune DiseaseBlood PlateletT-regulatory Cell +7

CD4⁺CD25⁺T cells responding to serologically defined autoantigens suppress antitumor immune responses

Hiroyoshi Nishikawa, Takuma Kato, Koji Tanida, +11

Proceedings of the National Academy of Sciences

Adaptive Immune SystemT-regulatory CellImmunologyPathologyAntigen Processing +16

Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS

Isao Tawara, Shinichi Kageyama, Yoshihiro Miyahara, +21

Blood

ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease

Jilu Zhang, Abdulraouf Ramadan, Brad Griesenauer, +8

Science Translational Medicine

Cell TherapyT-regulatory CellImmunologyImmune RegulationImmunologic Mechanism +20

Targeting of microRNA-142-3p in dendritic cells regulates endotoxin-induced mortality

Yaping Sun, Sooryanarayana Varambally, Christopher A. Maher, +10

Blood

Frequency of CD4+CD25hiFOXP3+ Regulatory T Cells Has Diagnostic and Prognostic Value as a Biomarker for Acute Graft-versus-Host-Disease

John Magenau, Xuemei Qin, Isao Tawara, +14

Biology of Blood and Marrow Transplantation

Cell TherapyT-regulatory CellImmunologyPathologyImmunotherapy +19