Concepedia

Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists

Xuqing Zhang, Heather R. Hufnagel, Cuifen Hou, Evan E. Opas, Sandra McKenney, Carl Crysler, John O’Neill, Dana L. Johnson, Zhihua Sui

Bioorganic & Medicinal Chemistry Letters · 2011 · 12 citations · 28 references

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References

28

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

Hiroyuki Kanda · Journal of Clinical Investigation · 2006 · 2.6K citations · Full text

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

Stuart P. Weisberg, Deborah Hunter, Reid Huber et al. · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

Stuart P. Weisberg · Journal of Clinical Investigation · 2006 · 1.4K citations · Full text

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Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance

Nozomu Kamei, Kazuyuki Tobe, Ryo Suzuki et al. · Journal of Biological Chemistry · 2006 · 900 citations · Full text

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Absence of Monocyte Chemoattractant Protein 1 in Mice Leads to Decreased Local Macrophage Recruitment and Antigen-Specific T Helper Cell Type 1 Immune Response in Experimental Autoimmune Encephalomyelitis

DeRen Huang, Jintang Wang, Pia Kivisäkk et al. · The Journal of Experimental Medicine · 2001 · 585 citations · Full text

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