Heather R. Hufnagel

Discovery of a 4-Azetidinyl-1-thiazoyl-cyclohexane CCR2 Antagonist as a Development Candidate

Xuqing Zhang, Cuifen Hou, Heather R. Hufnagel et al. · ACS Medicinal Chemistry Letters · 2012 · 21 citations · Full text

Combinatorial Chemistry, 4-Azetidinyl-1-thiazoyl-cyclohexane Ccr2 Antagonist, Immunology +18

Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists

Xuqing Zhang, Heather R. Hufnagel, Thomas Markotan et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 20 citations · Full text

Medicinal Chemistry, Heterocyclic, Biochemistry +11

Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

Jeremy Travins, Farah Ali, Hui Huang et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 18 citations · Full text

Combinatorial Chemistry, Medicine, Biphenylsulfonyl-thiophene-carboxamidine Inhibitors +4

A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s

Nalin L. Subasinghe, Jeremy Travins, Farah Ali et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 16 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Novel Series +10

Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists

Xuqing Zhang, Heather R. Hufnagel, Cuifen Hou et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 12 citations · Full text

Medicinal Chemistry, Heterocyclic, Medicine +7