Jeremy Travins

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

Fang Wang, Jeremy Travins, Byron DeLaBarre et al. · Science · 2013 · 797 citations

Medicine, Cancer Biology, Oncology +10

Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation

Peppi Koivunen, Sung-Woo Lee, Christopher G. Duncan et al. · Nature · 2012 · 722 citations · Full text

Medicine, Biochemistry, Metabolism +2

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

Supriya K. Saha, Christine A. Parachoniak, Krishna S. Ghanta et al. · Nature · 2014 · 469 citations

Medicine, Cancer Biology, Molecular Biology +14

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic <i>IDH2</i> Mutations

Katharine Yen, Jeremy Travins, Fang Wang et al. · Cancer Discovery · 2017 · 458 citations · Full text

Medicine, Oncology, Pharmacology +17

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Katya Marjon, Michael J. Cameron, Phong Quang et al. · Cell Reports · 2016 · 447 citations · Full text

Medicine, Cancer Biology, Oncology +17