Concepedia

Katya Marjon

KM

6

Publications

982

Citations

6

H-Index

2016

Active since

Affiliations

Agios Pharmaceuticals (United States)(Current)

Katya Marjon is an author at Agios Pharmaceuticals (United States) specializing in cancer biology, medicine, and cancer research.

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Publications per year

2016–2022

6

Publications

6

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Katya Marjon, Michael J. Cameron, Phong Quang et al. · Cell Reports · 2016 · 415 citations · Full text

MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage

Peter Kalev, Marc L. Hyer, Zenon Konteatis et al. · Cancer Cell · 2021 · 214 citations

, , +9

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Amaia Zabala‐Letona, Amaia Arruabarrena-Aristorena, Natalia Martín-Martín et al. · Nature · 2017 · 210 citations · Full text

, , +4

Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous <i>MTAP</i> Deletion

Zenon Konteatis, Jeremy Travins, Katya Marjon et al. · Journal of Medicinal Chemistry · 2021 · 88 citations · Full text

Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads

Mingzong Li, Zenon Konteatis, N. Nagaraja et al. · Journal of Medicinal Chemistry · 2022 · 33 citations · Full text

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