Concepedia

Katya Marjon

KM

Statistics

Publications

6

Citations

982

H-Index

6

Active since

2016

Affiliations

Agios Pharmaceuticals (United States)(Current)

Katya Marjon is an author at Agios Pharmaceuticals (United States) specializing in cancer biology, medicine, and cancer research.

Top concepts

Publications per year

2016–2022

6

Publications

6

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Katya Marjon, Michael J. Cameron, Phong Quang et al. · Cell Reports · 2016 · 415 citations · Full text

MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage

Peter Kalev, Marc L. Hyer, Zenon Konteatis et al. · Cancer Cell · 2021 · 214 citations

, , +9

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Amaia Zabala‐Letona, Amaia Arruabarrena-Aristorena, Natalia Martín-Martín et al. · Nature · 2017 · 210 citations · Full text

, , +4

Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous <i>MTAP</i> Deletion

Zenon Konteatis, Jeremy Travins, Katya Marjon et al. · Journal of Medicinal Chemistry · 2021 · 88 citations · Full text

Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads

Mingzong Li, Zenon Konteatis, N. Nagaraja et al. · Journal of Medicinal Chemistry · 2022 · 33 citations · Full text

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