Zenon Konteatis

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic <i>IDH2</i> Mutations

Katharine Yen, Jeremy Travins, Fang Wang et al. · Cancer Discovery · 2017 · 458 citations · Full text

Medicine, Oncology, Pharmacology +17

MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis

Katya Marjon, Michael J. Cameron, Phong Quang et al. · Cell Reports · 2016 · 447 citations · Full text

Medicine, Cancer Biology, Oncology +17

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Andrew M. Intlekofer, Alan H. Shih, Bo Wang et al. · Nature · 2018 · 280 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Two-site binding of C5a by its receptor: analternative binding paradigm for G protein-coupled receptors.

Salvatore Siciliano, Thomas E. Rollins, Julie A. DeMartino et al. · Proceedings of the National Academy of Sciences · 1994 · 235 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage

Peter Kalev, Marc L. Hyer, Zenon Konteatis et al. · Cancer Cell · 2021 · 234 citations

Life Sciences, Molecular Biology, Oncology +7