Concepedia

Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection

Thien-Duc Tran, David C. Pryde, Peter Jones, Fiona M. Adam, Neil Benson, Gerwyn Bish, Frederick Calo, Guiseppe Ciaramella, Rachel Dixon, Jonathan Duckworth,

Bioorganic & Medicinal Chemistry Letters · 2011 · 27 citations · 9 references

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References

9

Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy

Avidan U. Neumann, Nancy P. Lam, Harel Dahari et al. · Science · 1998 · 2.1K citations

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Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7

Jong‐Dae Lee, Tsung‐Hsien Chuang, Vanessa Redecke et al. · Proceedings of the National Academy of Sciences · 2003 · 586 citations · Full text

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An Extremely Active Catalyst for the Negishi Cross-Coupling Reaction

Jacqueline E. Milne, Stephen L. Buchwald · Journal of the American Chemical Society · 2004 · 431 citations

, , +17

A Novel Strategy for Physiologically Based Predictions of Human Pharmacokinetics

Hannah M. Jones, Neil Parrott, Karin Jorga et al. · Clinical Pharmacokinetics · 2006 · 348 citations

, , +14

Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery

David C. Pryde, Deepak Dalvie, Qiyue Hu et al. · Journal of Medicinal Chemistry · 2010 · 346 citations · Full text

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