Deepak Dalvie

Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery

David C. Pryde, Deepak Dalvie, Qiyue Hu et al. · Journal of Medicinal Chemistry · 2010 · 346 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +10

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

Phillip A. Schwartz, Petr Kuzmič, James Solowiej et al. · Proceedings of the National Academy of Sciences · 2013 · 281 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals

H. James Harwood, Stephen F. Petras, Lorraine D. Shelly et al. · Journal of Biological Chemistry · 2003 · 243 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Assessment of Three Human in Vitro Systems in the Generation of Major Human Excretory and Circulating Metabolites

Deepak Dalvie, R. Scott Obach, Ping Kang et al. · Chemical Research in Toxicology · 2009 · 187 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1<i>H</i>-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

Stefano Crosignani, Patrick Bingham, Pauline Bottemanne et al. · Journal of Medicinal Chemistry · 2017 · 138 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12