James Solowiej

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors

Michele McTigue, Brion W. Murray, Jeffrey H. Chen et al. · Proceedings of the National Academy of Sciences · 2012 · 538 citations · Full text

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Robert L. Hoffman, Robert S. Kania, Mary A. Brothers et al. · Journal of Medicinal Chemistry · 2020 · 518 citations · Full text

Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance

Ping Chen, Nathan V. Lee, Wenyue Hu et al. · Molecular Cancer Therapeutics · 2016 · 414 citations

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance

Phillip A. Schwartz, Petr Kuzmič, James Solowiej et al. · Proceedings of the National Academy of Sciences · 2013 · 271 citations · Full text

Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

Kevin D. Freeman‐Cook, Robert L. Hoffman, Nichol Miller et al. · Cancer Cell · 2021 · 172 citations

Tumor Biology, Oncology, Cdk2/4/6 Inhibitor +10