Gerwyn Bish

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Paul V. Fish, P. Filippakopoulos, Gerwyn Bish et al. · Journal of Medicinal Chemistry · 2012 · 195 citations · Full text

Histone Modifications, Pharmaceutical Science, Drug Target +20

Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

Jonathan D. Hargrave, Jennifer Herbert, Gerwyn Bish et al. · Organic & Biomolecular Chemistry · 2006 · 30 citations

Microwave Reactor, Engineering, Alkene Metathesis +9

N-(1,2-Diphenylethyl)piperazines: A new class of dual serotonin/noradrenaline reuptake inhibitor

M. Jonathan Fray, Gerwyn Bish, Alan D. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 29 citations · Full text

Medicinal Chemistry, Medicine, Neuropharmacology +6

Peptide modification through site-selective residue interconversion: application of the rhodium-catalysed 1,4-addition of aryl siloxanes and boronates

C. J. Chapman, Jonathan D. Hargrave, Gerwyn Bish et al. · Tetrahedron · 2008 · 29 citations

Engineering, Biochemistry, Natural Sciences +9

Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection

Thien-Duc Tran, David C. Pryde, Peter Jones et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 27 citations · Full text

Hepatology, Viral Hepatitis, Immunology +9