Paul V. Fish

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

Dustin J. Flanagan, Nalle Pentinmikko, Kalle Luopajärvi et al. · Nature · 2021 · 252 citations · Full text

Medicine, Cancer Biology, Oncology +12

PFI-1, a Highly Selective Protein Interaction Inhibitor, Targeting BET Bromodomains

S. Picaud, David Da Costa, Angeliki Thanasopoulou et al. · Cancer Research · 2013 · 247 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Paul V. Fish, P. Filippakopoulos, Gerwyn Bish et al. · Journal of Medicinal Chemistry · 2012 · 196 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

( <i>R</i> )-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

Dalia Baršytė-Lovejoy, Fengling Li, Menno J. Oudhoff et al. · Proceedings of the National Academy of Sciences · 2014 · 188 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +13

Predicting Penetration Across the Blood-Brain Barrier from Simple Descriptors and Fragmentation Schemes

Yuan H. Zhao, Michael H. Abraham, Adam Ibrahim et al. · Journal of Chemical Information and Modeling · 2006 · 140 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16