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Discovery of potential and selective COX-1 inhibitory leads using pharmacophore modelling, in silico screening and in vitro evaluation

Medicinal ChemistryPreclinical Drug EvaluationBiochemistryMedicineNatural SciencesRational Drug DesignPathologySelective Cox-1 InhibitoryPharmacotherapyDrug DevelopmentPharmacologySilico ScreeningVitro EvaluationDrug DiscoveryDrug Resistance