Robert Langenbach

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration

Robert Langenbach, Scott G. Morham, Howard F. Tiano et al. · Cell · 1995 · 1.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse

Scott G. Morham, Robert Langenbach, Charles D. Loftin et al. · Cell · 1995 · 1.1K citations · Full text

Medicine, Molecular Biology, Molecular Genetics +13

Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.

Patricia C. Chulada, Morrow B. Thompson, Joel F. Mahler et al. · PubMed · 2000 · 498 citations

Medicine, Molecular Biology, Oncology +13

Anovulation in Cyclooxygenase-2-Deficient Mice Is Restored by Prostaglandin E2 and Interleukin-1β*

Barbara J. Davis, David E. Lennard, Christopher A. Lee et al. · Endocrinology · 1999 · 348 citations · Full text

Medicine, Endocrinology, Physiology +17

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

Howard F. Tiano, Charles D. Loftin, Jackie Akunda et al. · PubMed · 2002 · 345 citations

Medicine, Dermatology, Cancer Pharmacology +7