Concepedia

Double Replacement Gene Targeting for the Production of a Series of Mouse Strains with Different Prion Protein Gene Alterations

Richard C. Moore, Nicola J. Redhead, Jim Selfridge, James Hope, Jean Manson, David W. Melton

Nature Biotechnology · 1995 · 65 citations · 39 references

DOI

Concepts

References

39

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.6K citations · Full text

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[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

Thomas A. Kunkel, John D. Roberts, Richard A. Zakour · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 5.3K citations

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Identification of the Cystic Fibrosis Gene: Genetic Analysis

Bat-Sheva Kerem, Johanna M. Rommens, Janet A. Buchanan et al. · Science · 1989 · 4.1K citations

, , +10

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

, , +16

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

Suzanne L. Mansour, Kirk R. Thomas, Mario R. Capecchi · Nature · 1988 · 1.7K citations

, , +15