[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

Studies on transformation of Escherichia coli with plasmids

Douglas Hanahan · Journal of Molecular Biology · 1983 · 11.2K citations

Bacteriology, Biotechnology, Escherichia Coli +4

IN VITRO MUTAGENESIS

Michael D. Smith · Annual Review of Genetics · 1985 · 334 citations

Genetics, Molecular Biology, Molecular Genetics +16

The mutational specificity of DNA polymerase-beta during in vitro DNA synthesis. Production of frameshift, base substitution, and deletion mutations.

Thomas A. Kunkel · Journal of Biological Chemistry · 1985 · 319 citations · Full text

Insertion of nucleotides opposite apurinic apyrimidinic sites in deoxyribonucleic acid during in vitro synthesis: uniqueness of adenine nucleotides

Daphna Sagher, Bernard S. Strauss · Biochemistry · 1983 · 318 citations

Deoxyuridine triphosphatase of Escherichia coli. Purification, properties, and use as a reagent to reduce uracil incorporation into DNA.

Joseph Shlomai, A Kornberg · Journal of Biological Chemistry · 1978 · 175 citations · Full text

Biosynthesis, Engineering, Biochemistry +10