Concepedia

Sequence-defined Mutagenesis

Sequence-Defined Mutagenesis is a mutagenesis strategy that belongs to the class of precision genome editing techniques, distinguished by its reliance on predetermined nucleotide sequences to direct specific, designed mutations at exact genomic loci.

121

Publications

16.1K

Citations

504

Authors

192

Institutions

Publications per year

2017–2026

10

Parents

Publications

121

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

Thomas A. Kunkel, John D. Roberts, Richard A. Zakour · Methods in enzymology on CD-ROM/Methods in enzymology · 1987 · 5.3K citations

, , +8

Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

Win Ping Deng, Jac A. Nickoloff · Analytical Biochemistry · 1992 · 1.1K citations

, , +11

An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli

Travis S. Young, Insha Ahmad, Jun Yin et al. · Journal of Molecular Biology · 2009 · 649 citations

, , +16

A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction

DW Leung, E Chen, Goeddel Dv · Medical Entomology and Zoology · 1989 · 612 citations

, , +13

Mutagenesis at a specific position in a DNA sequence.

Clyde A. Hutchison, Sierra Phillips, Marshall H. Edgell et al. · Journal of Biological Chemistry · 1978 · 521 citations · Full text

, , +15

1–5 of 121

Authors

504

  1. RP
    Robert P. Fuchs

    Centre National de la Recherche Scientifique, France

    5 publications · 309 citations

    5

    h-index

  2. TA
    Thomas A. Kunkel

    National Institute of Environmental Health Sciences, United States

    3 publications · 5.4K citations

    3

    h-index

  3. NK
    Nicole Koffel-Schwartz

    Centre National de la Recherche Scientifique, France

    3 publications · 114 citations

    3

    h-index

  4. MW
    M. Watanabe

    Suzuki (Japan), Japan

    2 publications · 59 citations

    2

    h-index

  5. TO
    Toshihiro Ohta

    Suzuki (Japan), Japan

    2 publications · 59 citations

    2

    h-index

1–5 of 504

Institutions

192

  1. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    21 publications

    1K citations

  2. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    38 publications

    11.4K citations

  3. Harvard University

    Cambridge, United States

    4 h-index

    10 publications

    2.7K citations

  4. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    14 publications

    5.4K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    7 publications

    370 citations

  6. National Institute of Health Sciences

    Tokyo, Japan

    3 h-index

    5 publications

    134 citations

  7. Shanghai Jiao Tong University

    Shanghai, China

    2 h-index

    6 publications

    2.6K citations

  8. National Institute of Environmental Health Sciences

    Durham, United States

    2 h-index

    2 publications

    36 citations

1–8 of 192

Venues

  1. Journal of Molecular Biology

    JMB · 10 publications · 1.6K citations

    10

    h-index

  2. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 9 publications · 5.7K citations

    9

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 556 citations

    6

    h-index

  4. Gene

    6 publications · 595 citations

    6

    h-index

  5. Nucleic Acids Research

    6 publications · 123 citations

    6

    h-index

1–5