Concepedia

Gene Targeting

Gene Targeting is a molecular genetics technique that enables the precise modification of a specific endogenous gene locus through the introduction of exogenous DNA sequences, distinguished from other gene manipulation methods by its reliance on homologous recombination to achieve site-specific integration.

907

Publications

92.6K

Citations

4.6K

Authors

1.1K

Institutions

Publications per year

2017–2026

123

Parents

Publications

907

Heterologous modules for efficient and versatile PCR-based gene targeting inSchizosaccharomyces pombe

Jürg Bähler, Jian‐Qiu Wu, Mark S. Longtine et al. · Yeast · 1998 · 2.3K citations

, , +17

Inducible Gene Targeting in Mice

Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text

, , +14

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

Martin F. Offield, Tom L. Jetton, Patricia A. Labosky et al. · Development · 1996 · 1.5K citations

, , +16

Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin

Jacob H. Hanna, Marius Wernig, Styliani Markoulaki et al. · Science · 2007 · 1.5K citations

, , +16

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

Ursula von Freeden-Jeffry, Paulo Vieira, Linda Lucian et al. · The Journal of Experimental Medicine · 1995 · 1.4K citations · Full text

, , +17

1–5 of 907

Authors

4.6K

  1. AB
    Allan Bradley

    Baylor College of Medicine, United States

    12 publications · 1.2K citations

    12

    h-index

  2. DW
    David W. Russell

    The University of Texas Southwestern Medical Center, United States

    9 publications · 692 citations

    9

    h-index

  3. JH
    John H. Wilson

    Baylor College of Medicine, United States

    8 publications · 415 citations

    8

    h-index

  4. PH
    Paul Hasty

    The University of Texas at San Antonio Health Science Center, United States

    8 publications · 701 citations

    8

    h-index

  5. MM
    Michael M. Seidman

    National Institute on Aging, United States

    7 publications · 347 citations

    7

    h-index

1–5 of 4.6K

Institutions

1.1K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    29 h-index

    115 publications

    22.5K citations

  2. Baylor College of Medicine

    Houston, United States

    24 h-index

    95 publications

    8.1K citations

  3. Harvard University

    Cambridge, United States

    23 h-index

    79 publications

    12.4K citations

  4. Johns Hopkins University

    Baltimore, United States

    16 h-index

    65 publications

    16.4K citations

  5. Kyoto University

    Kyoto, Japan

    15 h-index

    53 publications

    5.8K citations

  6. Stanford University

    Stanford, United States

    15 h-index

    43 publications

    3.9K citations

  7. University of Washington

    Seattle, United States

    15 h-index

    62 publications

    6.3K citations

  8. National Institutes of Health

    Bethesda, United States

    15 h-index

    64 publications

    5.5K citations

1–8 of 1.1K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 64 publications · 12.5K citations

    55

    h-index

  2. Molecular and Cellular Biology

    MCB · 61 publications · 6.1K citations

    41

    h-index

  3. Nucleic Acids Research

    54 publications · 2.8K citations

    30

    h-index

  4. PLoS ONE

    41 publications · 2.2K citations

    23

    h-index

  5. Scientific Reports

    19 publications · 1.8K citations

    18

    h-index

1–5