A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, +12

Cell

ChromatinDevelopmental BiologyChromatin StructureChromatin RemodelingMedicine +11

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe, +19

Nature

ChromatinChromatin StructureChromatin StateChromatin RemodelingNatural Sciences +10

Direct conversion of fibroblasts to functional neurons by defined factors

Thomas Vierbuchen, Austin Ostermeier, Zhiping P. Pang, +3

Nature

Direct ConversionNeuroregenerationMedicineNeural Stem CellFibroblast Growth Factor +7

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

Marius Wernig, Alexander Meissner, Ruth K. Foreman, +5

Nature

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellEngineeringMedicine +8

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Alexander Meissner, Tarjei S. Mikkelsen, Hongcang Gu, +10

Nature

ChromatinEpigenetic ChangeGeneticsDna MethylationEpigenomics +3

Polycomb complexes repress developmental regulators in murine embryonic stem cells

Laurie A. Boyer, Kathrin Plath, Julia Zeitlinger, +13

Nature

Lineage PlasticityDevelopmental BiologyMedicineStem Cell ResearchCell Fate Determination +5

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

Su‐Chun Zhang, Marius Wernig, Ian D. Duncan, +2

Nature Biotechnology

Regenerative MedicineEmbryonic Stem CellDevelopmental BiologyMedicineTransplantable Neural Precursors +13

Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

Yingsha Zhang, ChangHui Pak, Yan Han, +13

Neuron

Embryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicineInduced Pluripotent Stem Cells +11

Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin

Jacob H. Hanna, Marius Wernig, Styliani Markoulaki, +8

Science

Dissecting direct reprogramming through integrative genomic analysis

Tarjei S. Mikkelsen, Jacob H. Hanna, Xiaolan Zhang, +7

Nature

Functional GenomicsGene Sequence AnnotationGeneticsIntegrative Genomic AnalysisComputational Genomics +5