Concepedia

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

Marius Wernig, Alexander Meissner, Ruth K. Foreman, Tobias Brambrink, Manching Ku, Konrad Hochedlinger, B Bernstein, Rudolf Jaenisch

Nature · 2007 · 2.7K citations · 30 references

DOI

Concepts

References

30

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Kazutoshi Takahashi, Shinya Yamanaka · Cell · 2006 · 26.5K citations · Full text

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DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6.1K citations · Full text

, , +15

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie et al. · Cell · 2006 · 5.4K citations · Full text

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Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Laurie A. Boyer, Tong Ihn Lee, Megan F. Cole et al. · Cell · 2005 · 4.5K citations · Full text

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 4K citations

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