In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

Marius Wernig, Alexander Meissner, Ruth K. Foreman, +5

Nature

Tissue EngineeringRegenerative MedicineInduced Pluripotent Stem CellEngineeringMedicine +8

Disease-Specific Induced Pluripotent Stem Cells

In-Hyun Park, Natasha Arora, Hongguang Huo, +7

Cell

Regenerative MedicineInduced Pluripotent Stem CellMedicineInduced Pluripotent Stem CellsStem Cell Research +4

Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution

Nimet Maherali, Rupa Sridharan, Wei Xie, +9

Cell stem cell

ChromatinDevelopmental BiologyCardiac ReprogrammingWidespread Tissue ContributionChromatin Remodeling +9

Induced Pluripotent Stem Cells Generated Without Viral Integration

Matthias Stadtfeld, Masaki Nagaya, Jochen Utikal, +2

Science

Transcription Factors Oct4ImmunologyRegenerative MedicinePluripotent Stem CellsInduced Pluripotent Stem Cells +14

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

José M. Polo, Susanna Liu, María E. Figueroa, +12

Nature Biotechnology

Origin InfluencesInduced Pluripotent Stem CellDevelopmental BiologyPluripotent Stem CellsMedicine +8

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

José M. Polo, Endre Anderssen, Ryan Walsh, +17

Cell

Human CellInduced Pluripotent Stem CellCell ReprogrammingMolecular BiologyStem Cell Research +4

Ectopic Expression of Oct-4 Blocks Progenitor-Cell Differentiation and Causes Dysplasia in Epithelial Tissues

Konrad Hochedlinger, Yasuhiro Yamada, Caroline Beard, +1

Cell

Lineage PlasticityCell LineageDevelopmental BiologyEctopic ExpressionMorphogenesis +6

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

Jochen Utikal, José M. Polo, Matthias Stadtfeld, +6

Nature

Induced Pluripotent Stem CellDevelopmental BiologyCell InteractionCell ReprogrammingCellular Senescence +3

Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

Matthias Stadtfeld, Nimet Maherali, David T. Breault, +1

Cell stem cell

Induced Pluripotent Stem CellDevelopmental BiologyMedicineCell ReprogrammingStem Cell Research +6

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

Geoffrey Schiebinger, Jian Shu, Marcin Tabaka, +15

Cell

Cell LineageDevelopmental BiologyOptimal-transport AnalysisEngineeringSingle Cell Sequencing +11