Concepedia

Concept

induced pluripotent stem cells

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1.2K

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About

Induced pluripotent stem cells is a concept and methodology centered on the genetic reprogramming of differentiated somatic cells into a pluripotent state. This state, artificially induced through the expression of specific transcription factors, confers the ability to differentiate into any cell type of the three germ layers, effectively reverting cells to an embryonic stem cell-like state. As a research field, it investigates the molecular mechanisms governing cellular identity and plasticity, utilizing these reprogrammed cells as a significant tool for modeling human diseases, developing therapeutic strategies, and advancing regenerative medicine by providing an autologous source of various cell types.

Top Authors

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SY

Kyoto University

JC

Stanford University

JC

Salk Institute for Biological Studies

KT

Kyoto University

HR

Max Planck Institute for Molecular Biomedicine

Top Institutions

Rankings shown are based on concept H-Index.

Kyoto University

Kyoto, Japan

Harvard University

Cambridge, United States

Stanford University

Stanford, United States

Cambridge, United States

Johns Hopkins University

Baltimore, United States

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