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Functional analysis of human memory B-cell subpopulations: IgD+CD27+ B cells are crucial in secondary immune response by producing high affinity IgM

Autoimmune DiseaseAdaptive Immune SystemHumoral ResponseImmunologyImmunodominanceImmunologic MechanismSecondary Immune ResponseAutoimmunityHumoral ImmunityFunctional AnalysisImmunotherapyMedicineCell BiologyImmunological MemoryHigh Affinity Igm