Ralf Küppers

Pan-cancer analysis of whole genomes

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse et al. · Nature · 2020 · 3.1K citations · Full text

Human Immunoglobulin (Ig)M+IgD+ Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells

Ulf Klein, Klaus Rajewsky, Ralf Küppers · The Journal of Experimental Medicine · 1998 · 1.1K citations · Full text

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Laura Pasqualucci, Peter Neumeister, Tina Goossens et al. · Nature · 2001 · 1K citations

Lymphoid Neoplasia, Multiple Proto-oncogenes, Pathology +4

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

Holger Kanzler, Ralf Küppers, Martin‐Leo Hansmann et al. · The Journal of Experimental Medicine · 1996 · 752 citations · Full text

Lymphoid Neoplasia, Cell Lineage, Dominant Tumor Clone +15

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.

Ralf Küppers, Klaus Rajewsky, Min Zhao et al. · Proceedings of the National Academy of Sciences · 1994 · 685 citations · Full text

Lymphocyte Development, Immunodeficiencies, Immunology +21