Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

Life Sciences, Cell Biology, Oncology +16

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

Education, Cell Biology, Genetics +11

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

Carol W. Greider, Elizabeth H. Blackburn · Cell · 1985 · 3.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

Christopher M. Counter, Ariel A. Avilion, Catherine LeFeuvre et al. · The EMBO Journal · 1992 · 2.1K citations · Full text

Life Sciences, Cell Biology, Genetics +14

Telomere reduction in human colorectal carcinoma and with ageing

N D Hastie, Maureen Dempster, Malcolm G. Dunlop et al. · Nature · 1990 · 1.7K citations

Medicine, Cancer Biology, Oncology +14