Establishment of a novel monoclonal antibody against LGR5

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.6K citations

Cell Lineage, Cell Specialization, Marker Gene Lgr5 +10

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

Linda M. McLatchie, Neil J. Fraser, Martin J. Main et al. · Nature · 1998 · 2.1K citations

Calcitonin-receptor-like Receptor, Molecular Physiology, Signal Transduction +10

Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker, Rachel A. Ridgway, Johan H. van Es et al. · Nature · 2008 · 2.1K citations

Medicine, Adult Stem Cell, Stem Cell Research +4

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

Viljar Jaks, Nick Barker, Maria Kasper et al. · Nature Genetics · 2008 · 958 citations · Full text

Cell Lineage, Developmental Biology, Medicine +5

Engineered antibody Fc variants with enhanced effector function

Greg A. Lazar, Wei Dang, Sher Karki et al. · Proceedings of the National Academy of Sciences · 2006 · 783 citations · Full text

Engineered Fc Regions, Novel Therapy, Antibody Fc Variants +13