Dynamic association of tau with neuronal membranes is regulated by phosphorylation

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.

Inge Grundke‐Iqbal, Khurshid Iqbal, Y C Tung et al. · Proceedings of the National Academy of Sciences · 1986 · 3.6K citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner, Yazi D. Ke, Fabien Delerue et al. · Cell · 2010 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

GSK-3α regulates production of Alzheimer's disease amyloid-β peptides

Christopher J. Phiel, Virginia M.‐Y. Lee, Peter S. Klein · Nature · 2003 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +12

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

Michel Goedert, Claude M. Wischik, R. Anthony Crowther et al. · Proceedings of the National Academy of Sciences · 1988 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Neurobiology +13

Altered expression of synaptic proteins occurs early during progression of Alzheimer’s disease

Eliezer Masliah, Margaret Mallory, Michael Alford et al. · Neurology · 2001 · 749 citations · Full text

Life Sciences, Neurology, Neuroscience +15