Physiological release of endogenous tau is stimulated by neuronal activity

Amy M. Pooler, Emma Claire Phillips, Dawn H. W. Lau, +2

EMBO Reports

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture

Claire J. Garwood, Amy M. Pooler, Joseph Atherton, +2

Cell Death and Disease

Synaptic TransmissionImmunologyCell DeathAstrocytes AccompaniesNeurochemical Biomarkers +27

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

Amy M. Pooler, Manuela Polydoro, Eduardo A. Maury, +11

Acta Neuropathologica Communications

Dynamic association of tau with neuronal membranes is regulated by phosphorylation

Amy M. Pooler, Alessia Usardi, Catherine Evans, +3

Neurobiology of Aging

Neurodegenerative DiseasesNeuronal MembranesMolecular NeuroscienceSignal TransductionDegenerative Pathology +10

Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

Susanne Wegmann, Eduardo A. Maury, Molly J. Kirk, +13

The EMBO Journal

Neurodegenerative DiseasesAlzheimer's DiseaseDegenerative PathologyNeuroprotectionNeurology +4

Studying synapses in human brain with array tomography and electron microscopy

Kevin R. Kay, Colin Smith, Ann K. Wright, +12

Nature Protocols

Synaptic PlasticityElectron MicroscopyNeurophysiologyComputational NeuroscienceSynaptic Transmission +7

Uridine enhances neurite outgrowth in nerve growth factor-differentiated pheochromocytoma cells

Amy M. Pooler, D.H. Guez, R. Benedictus, +1

Neuroscience

UrologyDevelopmental BiologySignal TransductionPhysiologyPeripheral Nerve +3

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

Manuela Polydoro, Volodymyr Dzhala, Amy M. Pooler, +8

Acta Neuropathologica

Synaptic PlasticityNeurodegenerative DiseasesAlzheimer's DiseaseSynaptic NeuroscienceSynaptic Transmission +10

Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau

Alessia Usardi, Amy M. Pooler, Anjan Seereeram, +6

FEBS Journal

Synaptic TransmissionCellular LocalizationMolecular BiologyNeurochemical BiomarkersCytoskeleton +26

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease

Dawn H. W. Lau, Marte Hogseth, Emma Claire Phillips, +4

Acta Neuropathologica Communications