Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon, Manuela Polydoro, Marc Suárez‐Calvet, +9

Neuron

Neurodegenerative DiseasesAlzheimer's DiseaseTau PathologyDementiaEarly Alzheimer +9

Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology

Manuela Polydoro, Christopher M. Acker, Karen Duff, +2

Journal of Neuroscience

Brain FunctionTau PathologySynaptic TransmissionModerate Tau PathologySocial Sciences +18

αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

Becket Greten-Harrison, Manuela Polydoro, Megumi Morimoto‐Tomita, +8

Proceedings of the National Academy of Sciences

Synuclein ExpressionSynaptic TransmissionCellular NeurobiologySynaptic SignalingAge-dependent Neuronal Dysfunction +15

Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer’s disease

Amy M. Pooler, Manuela Polydoro, Eduardo A. Maury, +11

Acta Neuropathologica Communications

Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation

Cristiane Ritter, Michael Éverton Andrades, Mário Luís Conte da Frota, +8

Intensive Care Medicine

InflammationCecal LigationLipid PeroxidationPhysiologySepsis +6

Haloperidol- and clozapine-induced oxidative stress in the rat brain

Manuela Polydoro, Nadja Schröder, Maria Noêmia Martins de Lima, +7

Pharmacology Biochemistry and Behavior

MedicinePsychopharmacologyNeuropharmacologyNeurosciencePharmacology +4

Synaptic alterations in the rTg4510 mouse model of tauopathy

Katherine J. Kopeikina, Manuela Polydoro, Hwan‐Ching Tai, +5

The Journal of Comparative Neurology

Recognition memory impairment and brain oxidative stress induced by postnatal iron administration

Maria Noêmia Martins de Lima, Manuela Polydoro, Daniela Comparsi Laranja, +5

European Journal of Neuroscience

NeuropsychologyBrain FunctionBrain DevelopmentIron MetabolismIron Treatment +20

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

Manuela Polydoro, Volodymyr Dzhala, Amy M. Pooler, +8

Acta Neuropathologica

Synaptic PlasticityNeurodegenerative DiseasesAlzheimer's DiseaseSynaptic NeuroscienceSynaptic Transmission +10

Subcellular localization of tyrosine-nitrated proteins is dictated by reactive oxygen species generating enzymes and by proximity to nitric oxide synthase

Harry F.G. Heijnen, Elly van Donselaar, Jan W. Slot, +10

Free Radical Biology and Medicine

Cellular EnzymologyBiochemistryReactive Nitrogen SpecieNatural SciencesHeme Degradation +8