AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.4K citations

Life Sciences, Endocrinology, Pharmacology +16

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur, Kevin Pearson, Nathan L. Price et al. · Nature · 2006 · 4.2K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +11

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15