Étienne Lefai

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

Li Yu, Shanqin Xu, Maria M. Mihaylova et al. · Cell Metabolism · 2011 · 1.7K citations · Full text

Metabolic Syndrome, Inhibits Srebp Activity, Insulin Signaling +15

Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth

Chunming Cheng, Peng Ru, Feng Geng et al. · Cancer Cell · 2015 · 316 citations · Full text

Scap Is Essential, Signal Transduction, Biochemistry +11

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1–Mediated Lipogenesis

Feng Geng, Xiang Cheng, Xiaoning Wu et al. · Clinical Cancer Research · 2016 · 313 citations · Full text

Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice

Bérengère Benoit, Emmanuelle Meugnier, Martina Castelli et al. · Nature Medicine · 2017 · 219 citations

Fibrosis, Skeletal Muscle, Sarcopenia +6

Disruption of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Contributes to Muscle Insulin Resistance in Mice and Humans

Emily Tubbs, Stéphanie Chanon, Maud Robert et al. · Diabetes · 2018 · 188 citations

Mitochondrial Dysfunction, Whereas Skeletal Muscle, Metabolic Remodeling +19