Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 3.9K citations · Full text

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

Joyce J. Repa, Guosheng Liang, Jiafu Ou et al. · Genes & Development · 2000 · 1.7K citations · Full text

Oxysterol Receptors, Sterol Sensors, Transcriptional Regulation +16

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

Jay D. Horton, Nila Shah, Janet A. Warrington et al. · Proceedings of the National Academy of Sciences · 2003 · 1.4K citations · Full text

Genetics, Oligonucleotide Microarray Data, Srebp Isoform +16

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

Xiaodong Wang, Ryuichiro Sato, Michael S. Brown et al. · Cell · 1994 · 999 citations

Signal Transduction, Biochemistry, Natural Sciences +8

Crucial Step in Cholesterol Homeostasis

Tong Yang, Peter J. Espenshade, Michael E. Wright et al. · Cell · 2002 · 974 citations · Full text

Metabolic Syndrome, Oxysterol, Physiology +7