AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

Li Yu, Shanqin Xu, Maria M. Mihaylova, +12

Cell Metabolism

Metabolic SyndromeInhibits Srebp ActivityInsulin SignalingSignal TransductionBiochemistry +13

SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase

Xiuyun Hou, Shanqin Xu, Karlene A. Maitland-Toolan, +9

Journal of Biological Chemistry

Polyphenol-activated Sirt1Sirt1 FunctionsOxidative StressMetabolic SyndromeMetabolic Signaling +15

Polyphenols Stimulate AMP-Activated Protein Kinase, Lower Lipids, and Inhibit Accelerated Atherosclerosis in Diabetic LDL Receptor–Deficient Mice

Mengwei Zang, Shanqin Xu, Karlene A. Maitland-Toolan, +6

Diabetes

Role of NADPH Oxidase in the Vascular Hypertrophic and Oxidative Stress Response to Angiotensin II in Mice

Hui Di Wang, Shanqin Xu, Douglas G. Johns, +4

Circulation Research

HypertensionNadph OxidaseLipid PeroxidationAng IiRedox Biology +16

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

Yu Li, Shanqin Xu, Amber Giles, +9

The FASEB Journal

ImmunologyRapamycin Complex 1Fatty Liver DiseaseInsulin SignalingOxidative Stress +19

Temporal Control of NF-κB Activation by ERK Differentially Regulates Interleukin-1β-induced Gene Expression

Bingbing Jiang, Shanqin Xu, Xiuyun Hou, +3

Journal of Biological Chemistry

Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging

Shanqin Xu, Jia Ying, Bingbing Jiang, +9

American Journal of Physiology-Heart and Circulatory Physiology

Vascular DiseaseNitrosative StressMnsod NyRedox BiologyOxidative Stress +17

Antioxidant Improves Smooth Muscle Sarco/Endoplasmic Reticulum Ca ²⁺ -ATPase Function and Lowers Tyrosine Nitration in Hypercholesterolemia and Improves Nitric Oxide–Induced Relaxation

Takeshi Adachi, Reiko Matsui, Shanqin Xu, +5

Circulation Research

Redox SignalingLowers Tyrosine NitrationBiochemistryAtherosclerosisMedicine +13

Quantitative assessment of tyrosine nitration of manganese superoxide dismutase in angiotensin II-infused rat kidney

Wei Guo, Takeshi Adachi, Reiko Matsui, +6

American Journal of Physiology-Heart and Circulatory Physiology

Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II

Hui Di Wang, Douglas G. Johns, Shanqin Xu, +1

American Journal of Physiology-Heart and Circulatory Physiology

HypertensionNitric OxideRedox BiologyBlood PressureOxidative Stress +14