Concepedia

Thermo-targeted drug delivery of geldanamycin to hyperthermic tumor margins with diblock elastin-based biopolymers

Y. Chen, Pilju Youn, D.Y. Furgeson

Journal of Controlled Release · 2011 · 29 citations · 40 references

DOI

Concepts

References

40

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

, , +12

Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

S. Mark Roe, Chrisostomos Prodromou, Ronan O’Brien et al. · Journal of Medicinal Chemistry · 1999 · 999 citations · Full text

, , +14

Physical Chemistry of Biological Free Energy Transduction As Demonstrated by Elastic Protein-Based Polymers

Dan W. Urry · The Journal of Physical Chemistry B · 1997 · 843 citations

, , +17

Functional proteomic screens reveal an essential extracellular role for hsp90α in cancer cell invasiveness

Brenda K. Eustace, Takashi Sakurai, Jean K. Stewart et al. · Nature Cell Biology · 2004 · 595 citations

, , +12

Genetically Encoded Synthesis of Protein-Based Polymers with Precisely Specified Molecular Weight and Sequence by Recursive Directional Ligation:  Examples from the Elastin-like Polypeptide System

Dan E. Meyer, Ashutosh Chilkoti · Biomacromolecules · 2002 · 551 citations

, , +17