Hiroshi Maeda

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Pathology, Cancer Biology, Cancer Chemotherapy +17

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

Uma Prabhakar, Hiroshi Maeda, Rakesh K. Jain et al. · Cancer Research · 2013 · 1.4K citations

Nanoparticles, Workshop Discussions, Engineering +18

SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy

Hiroshi Maeda · Advanced Drug Delivery Reviews · 2001 · 652 citations

Polymer-drug Conjugate, Medicine, Polymer-conjugated Macromolecular Drugs +4

Tumoritropic and lymphotropic principles of macromolecular drugs.

Hiroshi Maeda, Yasuhiro Matsumura · PubMed · 1989 · 580 citations

Medicinal Chemistry, Mw 16, Drug Targeting +13

Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.bul.NO (nitric oxide) through a radical reaction

Takaaki Akaike, Masaki Yoshida, Yoichi Miyamoto et al. · Biochemistry · 1993 · 575 citations