Concepedia

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

Tibor Kempf, Alexander Zarbock, Christian Widera, Stefan Butz, Anika Stadtmann, Jan Rossaint, Matteo Bolomini‐Vittori, Mortimer Korf‐Klingebiel, L. Christian Napp, Birte Hansen,

Nature Medicine · 2011 · 517 citations · 40 references

DOI

Concepts

References

40

MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-β superfamily

Michelle Bootcov, Asne R. Bauskin, Stella M. Valenzuela et al. · Proceedings of the National Academy of Sciences · 1997 · 1.2K citations · Full text

, , +14

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

Stéphane Heymans, Aernout Luttun, Dieter Nuyens et al. · Nature Medicine · 1999 · 797 citations

, , +14

The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury

Tibor Kempf, Matthias Eden, Jens Strelau et al. · Circulation Research · 2006 · 641 citations

, , +15

Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

Motomu Shimaoka, Tsan Sam Xiao, Jin-huan Liu et al. · Cell · 2003 · 522 citations

, , +16

Periostin is essential for cardiac healingafter acute myocardial infarction

Masashi Shimazaki, Kazuto Nakamura, Isao Kii et al. · The Journal of Experimental Medicine · 2008 · 461 citations · Full text

, , +17