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Science

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GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice

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Nature Medicine

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Urinary TIMP-2 and IGFBP7 as Early Biomarkers of Acute Kidney Injury and Renal Recovery following Cardiac Surgery

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PLoS ONE

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

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Immunity

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Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap–mediated sterile inflammation

Jan Rossaint, Jan M. Herter, Hugo Van Aken, +5

Blood

FGF23 signaling impairs neutrophil recruitment and host defense during CKD

Jan Rossaint, Jessica Oehmichen, Hugo Van Aken, +5

Journal of Clinical Investigation

ImmunologyImmune RegulationPathologyRenal InflammationInnate Immunity +20

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

Craig T. Lefort, Jan Rossaint, Markus Moser, +7

Blood

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin

Maike Frye, Martina Dierkes, Verena Küppers, +9

The Journal of Experimental Medicine

Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response

Jan Rossaint, Katharina Kühne, Jennifer Skupski, +4

Nature Communications

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

Andre Broermann, Mark Winderlich, Helena Block, +8

The Journal of Experimental Medicine

Vascular DiseaseImmunologyBinding ProteinCellular PhysiologyInflammation +19