Concepedia

Different Nuclear Signals Are Activated by the B Cell Receptor during Positive Versus Negative Signaling

James I. Healy, Ricardo E. Dolmetsch, Luika Timmerman, Jason G. Cyster, Mathew L Thomas, Gerald R. Crabtree, Richard S. Lewis, Christopher C. Goodnow

Immunity · 1997 · 377 citations · 55 references

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55

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

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Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

Joël Raingeaud, Shashi Kumar Gupta, Jeffrey S. Rogers et al. · Journal of Biological Chemistry · 1995 · 2.2K citations · Full text

, , +17

A Cell Culture Model for T Lymphocyte Clonal Anergy

Ronald H. Schwartz · Science · 1990 · 1.9K citations

, , +17

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

Omar A. Coso, M Chiariello, Jin‐Chen Yu et al. · Cell · 1995 · 1.6K citations · Full text

, , +9

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

Neil A. Clipstone · Nature · 1992 · 1.6K citations

, , +12