Concepedia

Negative Selection

Negative selection is a molecular-level selection method that excludes undesired variants from a population by selectively eliminating or inactivating entities exhibiting specific target properties, thereby enriching the remaining pool with beneficial or neutral candidates.

2.1K

Publications

153.9K

Citations

9.1K

Authors

2.2K

Institutions

Publications per year

2017–2026

427

Parents

Publications

2.1K

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

, , +17

Not So Different After All: A Comparison of Methods for Detecting Amino Acid Sites Under Selection

Sergei L. Kosakovsky Pond, Simon D. W. Frost · Molecular Biology and Evolution · 2005 · 2.5K citations

, , +13

Evaluation of an Improved Branch-Site Likelihood Method for Detecting Positive Selection at the Molecular Level

J. Zhang · Molecular Biology and Evolution · 2005 · 1.9K citations · Full text

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Universal Patterns of Selection in Cancer and Somatic Tissues

Iñigo Martincorena, Keiran Raine, Moritz Gerstung et al. · Cell · 2017 · 1.7K citations · Full text

, , +15

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

Noemi Fusaki, Hiroshi Ban, Akiyo Nishiyama et al. · Proceedings of the Japan Academy Series B · 2009 · 1.4K citations · Full text

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1–5 of 2.1K

Authors

9.1K

  1. JS
    Jonathan Sprent

    Scripps Research Institute, United States

    14 publications · 2.3K citations

    14

    h-index

  2. GA
    Graham Anderson

    University of Birmingham, United Kingdom

    13 publications · 1K citations

    13

    h-index

  3. DD
    Dipankar Dasgupta

    University of Memphis, United States

    14 publications · 1.5K citations

    13

    h-index

  4. EJ
    Eric J. Jenkinson

    University of Birmingham, United Kingdom

    12 publications · 1.1K citations

    12

    h-index

  5. TL
    Tao Li

    Sichuan University, China

    13 publications · 346 citations

    12

    h-index

1–5 of 9.1K

Institutions

2.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    49 h-index

    235 publications

    39.5K citations

  2. Harvard University

    Cambridge, United States

    46 h-index

    304 publications

    42.6K citations

  3. National Institutes of Health

    Bethesda, United States

    40 h-index

    208 publications

    37.7K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    30 h-index

    161 publications

    7.9K citations

  5. University of California, San Francisco

    San Francisco, United States

    29 h-index

    123 publications

    11.8K citations

  6. Inserm

    Paris, France

    28 h-index

    172 publications

    8.8K citations

  7. University of California San Diego

    San Diego, United States

    27 h-index

    87 publications

    11.8K citations

  8. Stanford University

    Stanford, United States

    27 h-index

    125 publications

    15.2K citations

1–8 of 2.2K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 103 publications · 12.2K citations

    65

    h-index

  2. The Journal of Experimental Medicine

    105 publications · 12.1K citations

    60

    h-index

  3. The Journal of Immunology

    JI · 219 publications · 11.3K citations

    60

    h-index

  4. European Journal of Immunology

    EJI · 76 publications · 3.7K citations

    38

    h-index

  5. Science

    31 publications · 6.2K citations

    30

    h-index

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