Concepedia

The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators

Keiji Takahashi, Noriaki Hashimoto, Chisato Nakama, Kenji Kamata, Kaori Sasaki, Riki Yoshimoto, Sumika Ohyama, Hideka Hosaka, Hiroko Maruki, Yasufumi Nagata,

Bioorganic & Medicinal Chemistry · 2009 · 33 citations · 17 references

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17

The CCP4 suite: programs for protein crystallography

Number Collaborative Computational Project · Acta Crystallographica Section D Biological Crystallography · 1994 · 17.3K citations

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Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy

Joseph Grimsby, Ramakanth Sarabu, Wendy L. Corbett et al. · Science · 2003 · 537 citations

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Structural Basis for Allosteric Regulation of the Monomeric Allosteric Enzyme Human Glucokinase

Kenji Kamata, Morihiro Mitsuya, T. Nishimura et al. · Structure · 2004 · 503 citations · Full text

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Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

Franz M. Matschinsky · Diabetes · 1996 · 154 citations

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An Allosteric Activator of Glucokinase Impairs the Interaction of Glucokinase and Glucokinase Regulatory Protein and Regulates Glucose Metabolism

Mayumi Futamura, Hideka Hosaka, Akito Kadotani et al. · Journal of Biological Chemistry · 2006 · 101 citations · Full text

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