Aggressive Behavior and Altered Amounts of Brain Serotonin and Norepinephrine in Mice Lacking MAOA

Olivier Cases, Isabelle Seif, Joseph Grimsby, +7

Science

NeuropsychologyBrain SerotoninPsychopharmacologyMaoa DeficiencySocial Sciences +16

Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy

Joseph Grimsby, Ramakanth Sarabu, Wendy L. Corbett, +16

Science

Glucose AffinityGlycosylationMedicineInsulin ManagementDiabetes +13

LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor

Xuecai Ge, Hong Yang, Maria A. Bednarek, +13

Cell Metabolism

Molecular PhysiologySignal TransductionG Protein-coupled ReceptorMedicinePhysiology +5

Control of Pancreatic β Cell Regeneration by Glucose Metabolism

Shay Porat, Noa Weinberg-Corem, Sharona Tornovsky-Babaey, +16

Cell Metabolism

Glucose MetabolismDiabetesMedicineCell BiologyInsulin Signaling

The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy

Franz M. Matschinsky, Mark A. Magnuson, Dorothy Zelent, +5

Diabetes

Human monoamine oxidase A and B genes exhibit identical exon-intron organization.

Joseph Grimsby, Kevin Chen, L J Wang, +2

Proceedings of the National Academy of Sciences

GeneticsMolecular BiologyMolecular GeneticsExon 12Chemical Biology +15

Increased stress response and β–phenylethylamine in MAOB–deficient mice

Joseph Grimsby, Miklós Tóth, Takeshi Kumazawa, +5

Nature Genetics

Molecular PharmacologyMolecular NeuroscienceStressMedicinePhysiology +6

Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis

Michelle L. Boland, Rhianna C. Laker, KARLY M. MATHER, +17

Nature Metabolism

InflammationMetabolic SyndromeFibrosisGcgr Dual-agonist CotadutideHepatology +13

Robust anti‐obesity and metabolic effects of a dual <scp>GLP</scp> ‐1/glucagon receptor peptide agonist in rodents and non‐human primates

Susan Henderson, Anish Konkar, David C. Hornigold, +19

Diabetes Obesity and Metabolism

The Metabolism of Tyramine by Monoamine Oxidase A/B Causes Oxidative Damage to Mitochondrial DNA

Nils Hauptmann, Joseph Grimsby, Jean C. Shih, +1

Archives of Biochemistry and Biophysics

Aldehyde DehydrogenaseBiochemistryMitochondrial FunctionNatural SciencesMolecular Biology +6