β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir, +3

Diabetes

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

Yuval Dor, Juliana Brown, Olga I. Martinez, +1

Nature

Stem-cell DifferentiationCell LineageDevelopmental BiologyAdult Pancreatic β-CellsCell Specialization +8

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

Irina M. Conboy, Michael J. Conboy, Amy J. Wagers, +3

Nature

Regenerative MedicineLifespan ExtensionDevelopmental BiologyAgingLongevity +11

Feedback systems: an introduction for scientists and engineers

Karl Johan Åström, Richard M. Murray

Choice Reviews Online

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

Guoqiang Gu, Jolanta Dubauskaite, Douglas A. Melton

Development

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

Jeremy S. Duffield, Stuart J. Forbes, Christothea M. Constandinou, +6

Journal of Clinical Investigation

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

Jeremy S. Duffield, Stuart J. Forbes, Christothea M. Constandinou, +6

Journal of Clinical Investigation

Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

Catherine Postic, Masakazu Shiota, Kevin D. Niswender, +7

Journal of Biological Chemistry

Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction

M.Dodson Michael, Rohit Kulkarni, Catherine Postic, +4

Molecular Cell

Insulin ResistanceMetabolic SyndromeInsulin SignalingHepatologySevere Insulin Resistance +13

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

Fabrizio Thorel, Virginie Népote, Isabelle Avril, +4

Nature

Developmental BiologyPancreatic CancerMedicinePancreatic SurgeryExtreme β-Cell Loss +5