Intestinal lineage commitment of embryonic stem cells

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 6.9K citations

Regenerative Medicine, Cell Lineage, Crypt-villus Structures +9

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.6K citations

Cell Lineage, Cell Specialization, Marker Gene Lgr5 +10

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

Efficient differentiation of human embryonic stem cells to definitive endoderm

Kevin A. D’Amour, Alan D. Agulnick, Susan Eliazer et al. · Nature Biotechnology · 2005 · 1.7K citations

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +10

β-Catenin and TCF Mediate Cell Positioning in the Intestinal Epithelium by Controlling the Expression of EphB/EphrinB

Eduard Batlle, Jeffrey T. Henderson, Harry Beghtel et al. · Cell · 2002 · 1.1K citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +8