Concepedia

Lineage Commitment

Lineage Commitment is the developmental decision by which a cell restricts its potential to differentiate into a specific cell type or lineage, thereby becoming irreversibly directed toward a particular fate within the hierarchy of cellular differentiation.

809

Publications

99.8K

Citations

4.7K

Authors

968

Institutions

Publications per year

2017–2026

176

Parents

Children

Publications

809

Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment

Rowena McBeath, Dana M. Pirone, Celeste M. Nelson et al. · Developmental Cell · 2004 · 4.2K citations · Full text

, , +14

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

, , +13

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

Xuexian O. Yang, Bhanu P. Pappu, Roza Nurieva et al. · Immunity · 2008 · 1.6K citations · Full text

, , +13

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

Greg M. Delgoffe, Thomas P. Kole, Yan Zheng et al. · Immunity · 2009 · 1.3K citations · Full text

, , +14

Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment

Jennifer E. Phillips‐Cremins, Michael E.G. Sauria, Amartya Sanyal et al. · Cell · 2013 · 1.2K citations · Full text

, , +14

1–5 of 809

Authors

4.7K

  1. EV
    Ellen V. Rothenberg

    California Institute of Technology, United States

    16 publications · 2K citations

    16

    h-index

  2. AS
    Austin Smith

    Wellcome/MRC Cambridge Stem Cell Institute, United Kingdom

    9 publications · 2.5K citations

    9

    h-index

  3. CP
    Carsten Peterson

    Lund University, Sweden

    8 publications · 631 citations

    8

    h-index

  4. TE
    Tariq Enver

    University College London, United Kingdom

    8 publications · 2.2K citations

    8

    h-index

  5. SH
    Sui Huang

    Institute for Systems Biology, United States

    7 publications · 2.4K citations

    7

    h-index

1–5 of 4.7K

Institutions

968

  1. Harvard University

    Cambridge, United States

    41 h-index

    186 publications

    45.9K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    33 h-index

    138 publications

    30.9K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    29 h-index

    121 publications

    18.2K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    24 h-index

    77 publications

    25.2K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    129 publications

    10.4K citations

  6. Wellcome/MRC Cambridge Stem Cell Institute

    Cambridge, United Kingdom

    24 h-index

    93 publications

    15.6K citations

  7. Stanford University

    Stanford, United States

    22 h-index

    112 publications

    28.8K citations

  8. California Institute of Technology

    Pasadena, United States

    21 h-index

    80 publications

    9.9K citations

1–8 of 968

Venues

  1. Blood

    42 publications · 3.8K citations

    36

    h-index

  2. Development

    45 publications · 4.5K citations

    32

    h-index

  3. Developmental Biology

    35 publications · 3.1K citations

    29

    h-index

  4. Immunity

    26 publications · 9.2K citations

    25

    h-index

  5. Cell

    26 publications · 14.6K citations

    25

    h-index

1–5