Concepedia

Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling

Elissaveta Petrova, Jessica Rios-Esteves, Ouathek Ouerfelli, J. Fraser Glickman, Marilyn D. Resh

Nature Chemical Biology · 2013 · 159 citations · 20 references

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References

20

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Jussi Taipale, James Chen, Michael K. Cooper et al. · Nature · 2000 · 1.3K citations

, , +9

Structural Basis of Wnt Recognition by Frizzled

Claudia Y. Janda, Deepa Waghray, Aron M. Levin et al. · Science · 2012 · 876 citations

, , +17

A superfamily of membrane-bound O -acyltransferases with implications for Wnt signaling

Kay Hofmann · Trends in Biochemical Sciences · 2000 · 495 citations

, , +10

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

Miao-Hsueh Chen, Yajun Li, Takatoshi Kawakami et al. · Genes & Development · 2004 · 365 citations · Full text

, , +17